The treatment of iron-deficiency anaemia by iron-dextran infusion, with special reference to the effect on blood-grouping, coagulation, sedimentation and haemolysis.

Fifty patients with iron-deficiency anaemia were treated by total-dose infusion of iron-dextran. The therapeutic response was satisfactory in all cases. No severe systemic side effects occurred. In ten patients in whom detailed investigations were made there was no change in erythrocyte sedimentation rate or blood coagulation nor was there evidence of haemolysis following the irondextran infusion. No difficulty was found in ABO and Rh blood grouping and cross matching after infusion.